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Hong Kong-listed Insilico Medicine signs AI drug development deal with Eli Lilly

Reaching development, regulatory and commercial milestones could see value of deal hit around US$2.75 billion

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Life Star2, Insilico’s automation lab. Photo: Handout
Julie Zhang
Insilico Medicine has signed a potential multibillion-dollar deal with Eli Lilly to license out an early-stage drug pipeline and provide its artificial intelligence platform services in research and development collaborations.

Under the agreement announced on Monday, US-headquartered, Hong Kong-listed Insilico will receive an upfront payment of US$115 million. The deal could have a total value of around US$2.75 billion tied to development, regulatory and commercial milestones, plus tiered royalties on future sales.

Shares of Insilico surged 15 per cent to HK$65.75 at the open on Monday, before paring gains and closing at HK$58.70, up 2.6 per cent on the day.

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The drugs and their disease areas were not disclosed due to contract restrictions. However, Alex Zhavoronkov, the founder and CEO of 12-year-old Insilico, said that “some of those broad-spectrum, multi-target, multi-disease drugs may have been part of this deal”.

He said Insilico had been developing several drugs targeting fibrosis, inflammatory, oncology and other age-related pathways into clinical-stage development.

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“These assets could also be applied to oncology, cardiovascular and other disease areas,” Zhavoronkov said.

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