Stopping GLP-1 drugs like Ozempic often does not mean weight regain, US research suggests
New research suggests that many people who stop using GLP-1 drugs like Ozempic maintain their weight loss, countering previous studies
Many patients using highly effective GLP-1 drugs may not regain lost weight quickly when they stop treatment, according to an analysis of real-world data that sheds light on a chief concern about the therapies.
Their data runs counter to findings by Novo, based on the Danish drug maker’s clinical trials, that caution that many patients will soon regain lost weight if treatment is interrupted.
Obesity specialists have questioned whether people will need to use these medicines for years to maintain the benefits.
“The implication of our real-world evidence is not that rebound risk is negligible, but rather that durability is achievable in routine care,” Nference chief scientific officer Venky Soundararajan said.